Unique circulating microrna profile identified in early radiographic knee osteoarthritis
نویسندگان
چکیده
منابع مشابه
Early detection of radiographic knee osteoarthritis using computer-aided analysis.
OBJECTIVE To determine whether computer-based analysis can detect features predictive of osteoarthritis (OA) development in radiographically normal knees. METHOD A systematic computer-aided image analysis method weighted neighbor distances using a compound hierarchy of algorithms representing morphology (WND-CHARM) was used to analyze pairs of weight-bearing knee X-rays. Initial X-rays were a...
متن کاملFactors affecting radiographic progression of knee osteoarthritis.
OBJECTIVES To evaluate the prognostic significance of patient characteristics and radiographic features at the knee for outcome of knee osteoarthritis. METHODS This was a prospective observational study of 350 osteoarthritic knees. Clinical and radiographic data were obtained on 188 hospital referred patients (mean age 70, range 34-91 years). RESULTS Median duration of follow up was two yea...
متن کاملEarly knee osteoarthritis
Concepts regarding osteoarthritis, the most common joint disease, have dramatically changed in the past decade thanks to the development of new imaging techniques and the widespread use of arthroscopy that permits direct visualisation of intra-articular tissues and structure. MRI and ultrasound allow the early detection of pre-radiographic structural changes not only in the peri-articular bone ...
متن کاملGenetic, clinical and radiographic signs in knee osteoarthritis susceptibility
INTRODUCTION Osteoarthritis (OA) is considered to be a multifactorial and polygenic disease and diagnosis is mainly clinical and radiological. Correlation between radiographic data and clinical status has been reported. However, very few studies, especially in Caucasian people, describe the association between the Kellgren and Lawrence OA grading scale (KL) and genetic alterations to better und...
متن کاملAssociations between obesity and the radiographic phenotype in knee osteoarthritis.
BACKGROUND/AIM Investigation of the association between obesity and the distinction of radiographic patterns in knee osteoarthritis. MATERIALS AND METHODS Seven hundred and thirty-four women underwent weight-bearing antero-posterior knee radiography. Osteophytes and joint space narrowing (JSN) were graded according to the OARSI atlas. Each subject was assigned to one of the following groups w...
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ژورنال
عنوان ژورنال: Osteoarthritis and Cartilage
سال: 2020
ISSN: 1063-4584
DOI: 10.1016/j.joca.2020.02.087